<html>
<body>
<form>
<select id="mySelect" size="4">
<option>Apple</option>
<option>Pear</option>
<option>Banana</option>
<option>Orange</option>
</select>
</form>
<br>
<button onclick="myFunction()">Remove option with index "1"</button>
<script>
function myFunction() {
var x = document.getElementById("mySelect");
x.options.remove(1);
}
</script>
</body>
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</html>